Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC1114
Trial ID JPRN-jRCT1080225204
Disease Solid Tumor
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TAK-102
PhasePhase1
Recruitment statusRecruiting
TitleA Study of TAK-102 in Adult with Previously-Treated Solid Tumors
Year2020
CountryJapan
Company sponsorTakeda Pharmaceutical Company Limited
Other ID(s)NCT04405778|JapicCTI-205300

Clinical Result

Cohort1: dose level 1
Administration route intravenous infusion
Dosage 1E7 cells/body
Age Adult, Older_Adult
Cohort2: dose level 2
Administration route intravenous infusion
Dosage 1E8 cells/body
Age Adult, Older_Adult
Cohort3: dose level 3
Administration route intravenous infusion
Dosage 1E9 cells/body
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph