Basic Information

Gene symbol tk

GTO ID GTC1098
Trial ID IRCT20200502047277N3
Disease Glioblastoma
Altered gene tk
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment HSV-TK LV cells
PhasePhase2
Recruitment statusRecruiting
TitleIntracerebral Administration of Autologous Mesenchymal Stem Cells as HSV-TK Gene Vehicle to Treatment of Glioblastoma: Clinical Trial Phase II
Year2020
CountryIran (Islamic )
Company sponsorShahid Beheshti University of Medical Sciences
Vector information
Vectorlentivirus
Transgene/Inserted geneThymidine Kinase gene

Clinical Result

Cohort 1
Administration route intratumoral injection
Dosage 5E5 cells
Donor type autologous
Pts 20
Age Adult, Older_Adult

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