Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding | |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | Entrez:930 MIM:107265 HGNC:HGNC:1633 Ensembl:ENSG00000177455 AllianceGenome:HGNC:1633 | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding | |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | Entrez:933 MIM:107266 HGNC:HGNC:1643 Ensembl:ENSG00000012124 AllianceGenome:HGNC:1643 | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | |||||
Description | CD22 molecule |
GTO ID | GTC1077 |
Trial ID | ChiCTR-OPN-16008526 |
Disease | B-Cell Malignancy |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD22 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | An open-label, single-center and single-arm clinical study for sequential infusion of anti-CD22 and anti-CD19 CAR-T cells for patients with relapsed or refractory B-cell malignancies |
Year | 2016 |
Country | China |
Company sponsor | Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology |
Cohort 1 | |||||||
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