Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1077
Trial ID ChiCTR-OPN-16008526
Disease B-Cell Malignancy
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleAn open-label, single-center and single-arm clinical study for sequential infusion of anti-CD22 and anti-CD19 CAR-T cells for patients with relapsed or refractory B-cell malignancies
Year2016
CountryChina
Company sponsorDepartment of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Clinical Result

Cohort 1
Administration route None
Pts 400
Age Adult, Older_Adult

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