Gene symbol | EGFR | Synonyms | ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2 | Type of gene | protein-coding |
Chromosome | 7 | Map location | 7p11.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | epidermal growth factor receptor |
GTO ID | GTC1053 |
Trial ID | ChiCTR-OIN-16008252 |
Disease | Brain Glioma |
Altered gene | EGFR |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | EGFRvIII CAR-T cells |
Phase | Phase1 |
Recruitment status | Not Recruiting |
Title | An open-label, uncontrolled, single-arm pilot study to evaluate vascular interventional therapy mediated EGFRVIII-targeted chimeric antigen receptor T cells in advanced brain glioma |
Year | 2016 |
Country | China |
Company sponsor | Wuhan General Hospital of Guangzhou Command |
Cohort 1 | |||||||
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