Gene symbol | TNFRSF17 | Synonyms | BCM, BCMA, CD269, TNFRSF13A | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.13 | dbXrefs | |
Description | TNF receptor superfamily member 17 |
Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | SDC1 | Synonyms | CD138, SDC, SYND1, syndecan | Type of gene | protein-coding |
Chromosome | 2 | Map location | 2p24.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | syndecan 1 |
Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
Gene symbol | TNFRSF8 | Synonyms | CD30, D1S166E, Ki-1 | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1p36.22 | dbXrefs | |
Description | TNF receptor superfamily member 8 |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
Gene symbol | COLEC10 | Synonyms | 3MC3, CL-10, CL-34, CLL1 | Type of gene | protein-coding |
Chromosome | 8 | Map location | 8q24.12 | dbXrefs | |
Description | collectin subfamily member 10 |
GTO ID | GTC1043 |
Trial ID | ChiCTR-OIC-17013135 |
Disease | Hematologic Cancer |
Altered gene | CD19|CD20|CD22|CD33|CD123|CLL1|CD138|BCMA|CD30 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Chimeric Antigen Receptor T Cells (CART) Therapy in Refractory/Relapsed B cell hematologic malignancies including acute lymphoblastic leukemia (ALL), non-Hodgkin's lymphoma (NHL), multiple myeloma |
Year | 2017 |
Country | China |
Company sponsor | The third Xiangya Hospital of Central South University |
Cohort 1 | |||||||
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