Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding | |
Chromosome | 15 | Map location | 15q24.1 | dbXrefs | Entrez:80381 MIM:605715 HGNC:HGNC:19137 Ensembl:ENSG00000103855 AllianceGenome:HGNC:19137 | |
Description | CD276 molecule |
GTO ID | GTC1022 |
Trial ID | ChiCTR2300074342 |
Disease | Gastrointestinal Carcinoma |
Altered gene | CD276 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | B7-H3 CAR-T cells |
Co-treatment | Oncolytic adenovirus |
Phase | Phase1 |
Recruitment status | Not Recruiting |
Title | Clinical study of B7-H3 CAR-T combined with oncolytic adenovirus injection in the treatment of recurrent and refractory gastrointestinal neoplasms |
Year | 2023 |
Country | China |
Company sponsor | The Affiliated Hospital of Xuzhou Medical University |
Cohort 1 | |||||||
|