Gene symbol | TNFRSF10B | Synonyms | CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 | Type of gene | protein-coding |
Chromosome | 8 | Map location | 8p21.3 | dbXrefs | |
Description | TNF receptor superfamily member 10b |
Gene symbol | KLRK1 | Synonyms | CD314, D12S2489E, KLR, NKG2-D, NKG2D | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | killer cell lectin like receptor K1 |
GTO ID | GTC1019 |
Trial ID | ChiCTR2300071611 |
Disease | Advanced Tumor |
Altered gene | DR5|NKG2D |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | DR5/NKG2D CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Not Recruiting |
Title | The efficacy and safety of CAR-T cell injection in the treatment of advanced solid tumors -- an open, single center, single arm clinical study |
Year | 2023 |
Country | china |
Company sponsor | Shenzhen Hospital of Chinese Academy of Sciences |
Cohort 1 | |||||||
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