Basic Information

Gene symbol TNFRSF10B Synonyms CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 Type of gene protein-coding
Description TNF receptor superfamily member 10b

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC1019
Trial ID ChiCTR2300071611
Disease Advanced Tumor
Altered gene DR5|NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment DR5/NKG2D CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleThe efficacy and safety of CAR-T cell injection in the treatment of advanced solid tumors -- an open, single center, single arm clinical study
Year2023
Countrychina
Company sponsorShenzhen Hospital of Chinese Academy of Sciences

Clinical Result

Cohort 1
Administration route None
Pts 20
Age Adult, Older_Adult

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