Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
Gene symbol | CD38 | Synonyms | ADPRC 1, ADPRC1, cADPR1 | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4p15.32 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | CD38 molecule |
Gene symbol | CD7 | Synonyms | GP40, LEU-9, TP41, Tp40 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.3 | dbXrefs | |
Description | CD7 molecule |
Gene symbol | COLEC10 | Synonyms | 3MC3, CL-10, CL-34, CLL1 | Type of gene | protein-coding |
Chromosome | 8 | Map location | 8q24.12 | dbXrefs | |
Description | collectin subfamily member 10 |
GTO ID | GTC1009 |
Trial ID | ChiCTR2200062713 |
Disease | Acute Myeloid Leukemia |
Altered gene | CLL1|CD33|CD38|CD7 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD33/CD38/CD7/CLL1 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Not Recruiting |
Title | To evaluate the safety and efficacy of CLL1 /CD33/CD38/CD7 CAR-T in the treatment of relapsed and refractory acute myeloid leukemia |
Year | 2022 |
Country | China |
Company sponsor | Xuzhou Medical College affiliated hospital |
Cohort 1 | |||||||
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