| Gene symbol | FAP | Synonyms | DPPIV, FAPA, FAPalpha, SIMP | Type of gene | protein-coding |
| Chromosome | 2 | Map location | 2q24.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | fibroblast activation protein alpha | ||||
| Gene symbol | KLRK1 | Synonyms | CD314, D12S2489E, KLR, NKG2-D, NKG2D | Type of gene | protein-coding |
| Chromosome | 12 | Map location | 12p13.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | killer cell lectin like receptor K1 | ||||
| Gene symbol | FOLH1 | Synonyms | FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP | Type of gene | protein-coding |
| Chromosome | 11 | Map location | 11p11.12 | dbXrefs | |
| Description | folate hydrolase 1 | ||||
| GTO ID | GTC1008 |
| Trial ID | ChiCTR2200062549 |
| Disease | Prostate Cancer |
| Altered gene | PSMA|NKG2D|FAP |
| Therapeutic/Target gene | Target gene |
| Therapy | TCR-T cell |
| Treatment | PSMA/NKG2DL/FAP TCR-T cells |
| HLA | HLA-independent |
| Phase | Phase1|Phase2 |
| Recruitment status | Suspended |
| Title | A single-arm prospective study of Hi-TCR-T cells (secreting IL7, super IL15, CCL21, anti-PD-1 scFv, anti-TGF1 scFv) targeting PSMA/NKG2DL/FAP in the treatment of advanced prostate cancer |
| Year | 2022 |
| Country | China |
| Company sponsor | The Seventh Affiliated Hospital, Sun Yat-Sen University |
| Cohort 1 | |||||||
|
|||||||