Basic Information

Gene symbol ADGRE2 Synonyms CD312, CD97, EMR2, VBU Type of gene protein-coding
Description adhesion G protein-coupled receptor E2

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC1006
Trial ID ChiCTR2200061646
Disease Acute Myeloid Leukemia
Altered gene CLL1|CD33|ADGRE2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ADGRE2/CD33/CLL1 CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleTo evaluate the safety and efficacy of CLL1/CLL1+CD33/CD33/ADGRE2 CAR-T in the treatment of relapsed and refractory acute myeloid leukemia
Year2022
CountryChina
Company sponsorThe First Affiliated Hospital of Medical College of Zhejiang University

Clinical Result

Cohort 1
Administration route None
Pts 20
Age Child, Adult, Older_Adult

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