Basic Information

Gene symbol KRAS Synonyms C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description KRAS proto-oncogene, GTPase

GTO ID GTC1002
Trial ID ChiCTR2200061341
Disease Pancreatic Cancer
Altered gene KRAS
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment KRAS TCR-T cells
HLAHLA phenotype positive
PhasePhase1
Recruitment statusRecruiting
TitleAn exploring clinical research on evaluating the safety, efficiency and pharmacokinetics of KRAS mutated antigen-specific TCR-T cell therapy for advanced pancreatic cancer and other solid tumors
Year2022
CountryChina
Company sponsorSun Yat-sen Memorial Hospital, Sun Yat-sen University

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph