Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
Gene symbol | COLEC10 | Synonyms | 3MC3, CL-10, CL-34, CLL1 | Type of gene | protein-coding |
Chromosome | 8 | Map location | 8q24.12 | dbXrefs | |
Description | collectin subfamily member 10 |
GTO ID | GTC1000 |
Trial ID | ChiCTR2200061284 |
Disease | Acute Myeloid Leukemia |
Altered gene | CLL1|CD33 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Not Recruiting |
Title | A Single-arm, Open-label, Single-center Clinical Study: Safety, Tolerability and Preliminary Efficacy of Autologous Anti-CLL1/CLL1+CD33 CAR-T in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia in Children |
Year | 2022 |
Country | China |
Company sponsor | Sun Yat-sen Memorial Hospital, Sun Yat-sen University |
Cohort 1 | |||||||||
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