Basic Information

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC1000
Trial ID ChiCTR2200061284
Disease Acute Myeloid Leukemia
Altered gene CLL1|CD33
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleA Single-arm, Open-label, Single-center Clinical Study: Safety, Tolerability and Preliminary Efficacy of Autologous Anti-CLL1/CLL1+CD33 CAR-T in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia in Children
Year2022
CountryChina
Company sponsorSun Yat-sen Memorial Hospital, Sun Yat-sen University

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 18
Age Child

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