| Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding | |
| Chromosome | X|Y | Map location | X;Y | dbXrefs | Entrez:3563 MIM:308385 MIM:430000 HGNC:HGNC:6012 Ensembl:ENSG00000185291 Ensembl:ENSG00000292332 AllianceGenome:HGNC:6012 | |
| Description | interleukin 3 receptor subunit alpha | |||||
| Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding | |
| Chromosome | 19 | Map location | 19q13.41 | dbXrefs | Entrez:945 MIM:159590 HGNC:HGNC:1659 Ensembl:ENSG00000105383 AllianceGenome:HGNC:1659 | |
| Gene perturbation-related omics dataset | PerturbAtlas | |||||
| Description | CD33 molecule | |||||
| Gene symbol | COLEC10 | Synonyms | 3MC3, CL-10, CL-34, CLL1 | Type of gene | protein-coding | |
| Chromosome | 8 | Map location | 8q24.12 | dbXrefs | Entrez:10584 MIM:607620 HGNC:HGNC:2220 Ensembl:ENSG00000184374 AllianceGenome:HGNC:2220 | |
| Description | collectin subfamily member 10 | |||||
| GTO ID | GTC0994 |
| Trial ID | ChiCTR2200060215 |
| Disease | Acute Myeloid Leukemia |
| Altered gene | CLL1|CD33|CD123 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | CAR-T cells |
| Phase | Early_Phase1 |
| Recruitment status | Not Recruiting |
| Title | A single-arm, non-blind clinical study of safety and efficacy of autologous CLL1/CLL1 + CD33/CD123 CAR-T in the treatment of relapsed and refractory acute myeloid leukemia |
| Year | 2022 |
| Country | China |
| Company sponsor | The First Affiliated Hospital of Medical College of Zhejiang University |
| Cohort 1 | |||||||||
|
|||||||||