Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | claudin 18 |
GTO ID | GTC0985 |
Trial ID | ChiCTR2200058494 |
Disease | Solid Tumor |
Altered gene | CLDN18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CLDN18.2 CAR-T cells |
Phase | Phase1 |
Recruitment status | Not Recruiting |
Title | Clinical study of CLDN18.2-targeting chimeric antigen receptor-modified autologous T cells in advanced solid tumors with positive CLDN18.2 expression |
Year | 2022 |
Country | China |
Company sponsor | Shanghai Changhai Hospital |
Cohort 1 | |||||||||
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