Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC0981
Trial ID ChiCTR2200058044
Disease Acute Myeloid Leukemia
Altered gene CLL1|CD33|CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD123/CD33/CLL1 CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleA single-arm, unblinded clinical study of safety and efficacy of autogenous CLL1/CD33/CD123 CAR T in patients with relapsed and refractory acute myeloid leukemia
Year2022
CountryChina
Company sponsorHuizhou Municipal Central Hospital

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 10
Age Child, Adult, Older_Adult

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