Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
Gene symbol | COLEC10 | Synonyms | 3MC3, CL-10, CL-34, CLL1 | Type of gene | protein-coding |
Chromosome | 8 | Map location | 8q24.12 | dbXrefs | |
Description | collectin subfamily member 10 |
GTO ID | GTC0981 |
Trial ID | ChiCTR2200058044 |
Disease | Acute Myeloid Leukemia |
Altered gene | CLL1|CD33|CD123 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD123/CD33/CLL1 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Not Recruiting |
Title | A single-arm, unblinded clinical study of safety and efficacy of autogenous CLL1/CD33/CD123 CAR T in patients with relapsed and refractory acute myeloid leukemia |
Year | 2022 |
Country | China |
Company sponsor | Huizhou Municipal Central Hospital |
Cohort 1 | |||||||||
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