Basic Information

Gene symbol KRAS Synonyms C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description KRAS proto-oncogene, GTPase

GTO ID GTC0962
Trial ID ChiCTR2100054460
Disease Pancreatic Cancer
Altered gene KRAS
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment KRAS G12V TCR-T cells
HLAHLA-A*11:01
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleA clinical trial study for evaluating the efficacy of KRAS-mutated antigen-specific TCR T cell therapy for advanced pancreatic cancer
Year2021
CountryChina
Company sponsorJinling Hospital Affiliated to Nanjing University (Eastern Theater General Hospital)

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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