Basic Information

Gene symbol CLDN6 Synonyms None Type of gene protein-coding
Description claudin 6

Gene symbol MSLN Synonyms MPF, SMRP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mesothelin

Gene symbol MUC1 Synonyms ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mucin 1, cell surface associated

GTO ID GTC0953
Trial ID ChiCTR2100052760
Disease Lung Non-Small Cell Carcinoma
Altered gene CLDN6|MUC1|MSLN
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleSafety and efficacy of CLDN6/MUC1/MSLN CAR T cells in patients with advanced non-small cell lung cancer
Year2021
CountryChina
Company sponsorThe First Affiliated Hospital of Nanchang University

Clinical Result

Cohort 1
Administration route None
Pts 15
Age Adult, Older_Adult

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