Gene symbol | CLDN6 | Synonyms | None | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.3 | dbXrefs | |
Description | claudin 6 |
Gene symbol | MSLN | Synonyms | MPF, SMRP | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mesothelin |
Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q22 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mucin 1, cell surface associated |
GTO ID | GTC0953 |
Trial ID | ChiCTR2100052760 |
Disease | Lung Non-Small Cell Carcinoma |
Altered gene | CLDN6|MUC1|MSLN |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | Safety and efficacy of CLDN6/MUC1/MSLN CAR T cells in patients with advanced non-small cell lung cancer |
Year | 2021 |
Country | China |
Company sponsor | The First Affiliated Hospital of Nanchang University |
Cohort 1 | |||||||
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