Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC0949 |
Trial ID | ChiCTR2100052009 |
Disease | B-Cell Acute Lymphoblastic Leukemia |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD22 CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A clinical study on the safety and effectiveness of CD19 CAR-T and CD22 CAR-T sequential treatment of relapsed and refractory acute B lymphocytic leukemia |
Year | 2021 |
Country | China |
Company sponsor | the First Affiliated Hospital, Zhejiang University School of Medicine |
Cohort 1 | |||||||
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