| Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding |
| Chromosome | X | Map location | Xq26.2 | dbXrefs | |
| Description | glypican 3 | ||||
| Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
| Chromosome | 17 | Map location | 17q12 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | erb-b2 receptor tyrosine kinase 2 | ||||
| Gene symbol | MSLN | Synonyms | MPF, SMRP | Type of gene | protein-coding |
| Chromosome | 16 | Map location | 16p13.3 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | mesothelin | ||||
| Gene symbol | PSCA | Synonyms | PRO232, lncPSCA | Type of gene | protein-coding |
| Chromosome | 8 | Map location | 8q24.3 | dbXrefs | |
| Description | prostate stem cell antigen | ||||
| Gene symbol | TGFB1 | Synonyms | CED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta | Type of gene | protein-coding |
| Chromosome | 19 | Map location | 19q13.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | transforming growth factor beta 1 | ||||
| GTO ID | GTC0935 |
| Trial ID | ChiCTR2100047638 |
| Disease | Lung Non-Small Cell Carcinoma |
| Altered gene | MSLN|PSCA|HER2|GPC3|TGFB1 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | CAR-T cells |
| Phase | Early_Phase1 |
| Recruitment status | Not Recruiting |
| Title | CAR-T Cells Targeting MSLN/PSCA/HER2/GPC3/TGF-β as a Third-line or Further Treatment for Advanced Non-Small Cell Lung Cancer: An Exploratory Study |
| Year | 2021 |
| Country | China |
| Company sponsor | The First People's Hospital of Foshan |
| Cohort 1 | |||||||
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