Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC0908
Trial ID ChiCTR2000041347
Disease Head and Neck Squamous Cell Carcinoma
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD70 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitlePhase I Clinical Study on the Safety and Efficacy of CD70 CAR-T Cells for Head and Neck Squamous Cell Carcinoma Failing Standard Treatment
Year2020
CountryChina
Company sponsorThe Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University

Clinical Result

Cohort 1
Administration route intratumoral injection
Dosage 3E7 cells, 3E8 cells
Pts 6

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