Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC0898
Trial ID ChiCTR2000040665
Disease B-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleDonor fully human CD19/CD22 dual target CAR T cells combined with allogeneic hematopoietic stem cell transplantation for the treatment of adult refractory/relapsed B-cell lymphoma. Single-center, open, non-randomized, single-arm clinical trial
Year2020
CountryChina
Company sponsorBeijing Boren Hospital

Clinical Result

Cohort 1
Administration route None
Pts 20
Age Adult, Older_Adult

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