Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

GTO ID GTC0894
Trial ID ChiCTR2000040261
Disease Abdominal Metastatic Malignant Tumor
Altered gene CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TX103 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleClinical trial of TX103-CAR-T cells in the treatment of abdominal metastatic malignant tumor
Year2020
CountryChina
Company sponsorFujian Medical University Union Hospital

Clinical Result

Cohort1: incremental dose
Administration route None
Dosage 1E8 cells/kg, 4.5E8 cells/kg, 1E9 cells/kg, 2E9 cells/kg
Pts 12
Age Adult, Older_Adult
Cohort2: decremental dose
Administration route None
Dosage 9E7 cells/kg, 3E8 cells/kg, 8E8 cells/kg, 1.5E9 cells/kg
Pts 12
Age Adult, Older_Adult

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