| Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding | |
| Chromosome | 16 | Map location | 16p11.2 | dbXrefs | Entrez:930 MIM:107265 HGNC:HGNC:1633 Ensembl:ENSG00000177455 AllianceGenome:HGNC:1633 | |
| Description | CD19 molecule | |||||
| Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding | |
| Chromosome | 19 | Map location | 19q13.12 | dbXrefs | Entrez:933 MIM:107266 HGNC:HGNC:1643 Ensembl:ENSG00000012124 AllianceGenome:HGNC:1643 | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | |||||
| Description | CD22 molecule | |||||
| GTO ID | GTC0888 |
| Trial ID | ChiCTR2000038641 |
| Disease | B-Cell Acute Lymphoblastic Leukemia | B-Cell Malignancy |
| Altered gene | CD19|CD22 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | CT120 |
| Phase | Early_Phase1 |
| Recruitment status | Not Recruiting |
| Title | A single-arm clinical trial to assess the safety and efficacy of fully human anti-CD19XCD22 bispecific chimeric antigen receptor (CAR) T cells (CT120) for the treatment of relapsed/refractory B-cell malignancies |
| Year | 2020 |
| Country | China |
| Company sponsor | Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| Cohort1: B-ALL | |||||||||
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| Cohort2: BCL | |||||||||
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