Gene symbol | KLRK1 | Synonyms | CD314, D12S2489E, KLR, NKG2-D, NKG2D | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | killer cell lectin like receptor K1 |
GTO ID | GTC0885 |
Trial ID | ChiCTR2000038015 |
Disease | NKG2DL+ Tumor |
Altered gene | NKG2D |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | NKG2D CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | One-Center, Open-Label, Single-Arm Clinical Study of the Safety and Effectiveness of NKG2D CAR-T Cells Infusion in the Treatment of Relapsed or Refractory NKG2DL+ Tumors |
Year | 2020 |
Country | China |
Company sponsor | The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital |
Cohort 1 | |||||||
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