Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq26.2 | dbXrefs | |
Description | glypican 3 |
GTO ID | GTC0883 |
Trial ID | ChiCTR2000036458 |
Disease | Hepatocellular Carcinoma |
Altered gene | GPC3 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | GPC3 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | A phase I-IIa clinical study offourth-generation chimeric antigen receptor modified autologous T cells targeting phosphatidylinositol proteoglycan-3 (GPC3) for advanced hepatocellular carcinoma |
Year | 2020 |
Country | China |
Company sponsor | Zhongshan Hospital, Fudan University |
Cohort 1 | |||||||||
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