Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC0883
Trial ID ChiCTR2000036458
Disease Hepatocellular Carcinoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GPC3 CAR-T cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleA phase I-IIa clinical study offourth-generation chimeric antigen receptor modified autologous T cells targeting phosphatidylinositol proteoglycan-3 (GPC3) for advanced hepatocellular carcinoma
Year2020
CountryChina
Company sponsorZhongshan Hospital, Fudan University

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 5
Age Adult, Older_Adult

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