Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol SDC1 Synonyms CD138, SDC, SYND1, syndecan Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description syndecan 1

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

Gene symbol TNFRSF8 Synonyms CD30, D1S166E, Ki-1 Type of gene protein-coding
Description TNF receptor superfamily member 8

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC0881
Trial ID ChiCTR2000036350
Disease Hematologic Cancer
Altered gene CD19|CD20|CD22|CD33|CD123|CLL1|CD138|BCMA|CD30
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleAn unblinded, uncontrolled, single-center preliminary clinical study to evaluate the safety and efficacy of chimeric antigen-receptor engineered T cell immunotherapy (CART) targeting CD19/CD20/CD22/CD33/CD123/CLL-1/ CD138/BCMA/ CD30 and other cell surface biomarkers in the treatment of hematologic malignancies with positive corresponding biom
Year2020
CountryChina
Company sponsorThe Third Xiangya Hospital of Central South University

Clinical Result

Cohort 1
Administration route None
Pts 100
Age Child, Adult, Older_Adult

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