Gene symbol | MSLN | Synonyms | MPF, SMRP | Type of gene | protein-coding | |
Chromosome | 16 | Map location | 16p13.3 | dbXrefs | Entrez:10232 MIM:601051 HGNC:HGNC:7371 Ensembl:ENSG00000102854 AllianceGenome:HGNC:7371 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | mesothelin |
GTO ID | GTC0877 |
Trial ID | ChiCTR2000035549 |
Disease | Advanced Solid Tumor |
Altered gene | MSLN |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | MSLN CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | An exploratory study of aPD1-MSLN-CAR T cells for the treatment of MSLN-positive advanced solid tumors |
Year | 2020 |
Country | China |
Company sponsor | Shanghai Tenth People's Hospital |
Cohort 1 | |||||||
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