Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol CLEC12A Synonyms CD371, CLL-1, CLL1, DCAL-2, MICL Type of gene protein-coding
Description C-type lectin domain family 12 member A

GTO ID GTC0874
Trial ID ChiCTR2000034763
Disease Acute Myeloid Leukemia
Altered gene CD371|CD33|CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD123/CD33/CD371 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleCD371/33/123-CAR T cell combination therapy for refractory/relapsed acute myeloid leukemia in children: a single-center, open, non-random, single-arm clinical trial
Year2020
CountryChina
Company sponsorBeijing Boren Hospital

Clinical Result

Cohort 1
Administration route None
Pts 20
Age Child

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