Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
Gene symbol | CLEC12A | Synonyms | CD371, CLL-1, CLL1, DCAL-2, MICL | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.31-p13.2 | dbXrefs | |
Description | C-type lectin domain family 12 member A |
GTO ID | GTC0874 |
Trial ID | ChiCTR2000034763 |
Disease | Acute Myeloid Leukemia |
Altered gene | CD371|CD33|CD123 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD123/CD33/CD371 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | CD371/33/123-CAR T cell combination therapy for refractory/relapsed acute myeloid leukemia in children: a single-center, open, non-random, single-arm clinical trial |
Year | 2020 |
Country | China |
Company sponsor | Beijing Boren Hospital |
Cohort 1 | |||||||
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