Basic Information

Gene symbol EPCAM Synonyms Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1 Type of gene protein-coding
Description epithelial cell adhesion molecule

Gene symbol TM4SF1 Synonyms H-L6, L6, M3S1, TAAL6 Type of gene protein-coding
Description transmembrane 4 L six family member 1

GTO ID GTC0851
Trial ID ChiCTR2000030274
Disease Solid Tumor
Altered gene TM4SF1|EpCAM
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TM4SF1/EpCAM CAR-T cells
Recruitment statusNot Recruiting
TitleA clinical study on the safety and efficacy of chimeric antigen receptor T-cell therapy for the TM4SF1- and EpCAM-positive recurrent/refractory solid tumors
Year2020
CountryChina
Company sponsorShanghai 10th People's Hospital

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 18
Age Adult, Older_Adult

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