Gene symbol | EPCAM | Synonyms | Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1 | Type of gene | protein-coding |
Chromosome | 2 | Map location | 2p21 | dbXrefs | |
Description | epithelial cell adhesion molecule |
Gene symbol | TM4SF1 | Synonyms | H-L6, L6, M3S1, TAAL6 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q25.1 | dbXrefs | |
Description | transmembrane 4 L six family member 1 |
GTO ID | GTC0851 |
Trial ID | ChiCTR2000030274 |
Disease | Solid Tumor |
Altered gene | TM4SF1|EpCAM |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | TM4SF1/EpCAM CAR-T cells |
Recruitment status | Not Recruiting |
Title | A clinical study on the safety and efficacy of chimeric antigen receptor T-cell therapy for the TM4SF1- and EpCAM-positive recurrent/refractory solid tumors |
Year | 2020 |
Country | China |
Company sponsor | Shanghai 10th People's Hospital |
Cohort 1 | |||||||||
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