Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC0844 |
Trial ID | ChiCTR2000028826 |
Disease | Multiple Myeloma |
Altered gene | CD19|CD20|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | Clinical study for CD20-targeting iNKT cells and anti-CD19/CD22 CAR-T cells in the treatment of refractory or relapse AIDS-related B-cell lymphoma |
Year | 2020 |
Country | China |
Company sponsor | Shanghai Public Health Clinical Center |
Cohort1: CD20-targeting iNKT cells | |||||||
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Cohort2: anti-CD19/CD22 CAR-T cells | |||||||
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Cohort3: anti-CD19/CD22 CAR-T cells combined with HIV-specific CAR-T cells | |||||||
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Cohort4: HIV-specific CAR-T cells | |||||||
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