Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC0837
Trial ID ChiCTR1900028040
Disease Acute Myeloid Leukemia
Altered gene CD123|NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD123/NKG2D CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleClinical study on CD123 & NKG2D dual target CAR-T in the treatment of acute myeloid leukemia
Year2019
CountryChina
Company sponsorTianjin First Central Hospital

Clinical Result

Cohort 1
Administration route None
Donor type Allogeneic
Pts 40
Age Child, Adult, Older_Adult

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