Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | IL15 | Synonyms | IL-15 | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q31.21 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | interleukin 15 |
GTO ID | GTC0825 |
Trial ID | ChiCTR1900026083 |
Disease | B-Cell Malignancy |
Altered gene | CD19|CD20|IL15 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | ICG132|ICG134 |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | CD19/CD20/CARVAC-targeted Chimeric antigen receptor gene-modified T cells therapy in Patients with relapsed/refractory B cell malignancies |
Year | 2019 |
Country | China |
Company sponsor | The First Affiliated Hospital of Xiamen University |
Vector information | |||||
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Cohort1: ICG132 | |||||||||
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Cohort2: ICG134 | |||||||||
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