Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC0815
Trial ID ChiCTR1900025089
Disease B-Cell Acute Lymphoblastic Leukemia | Diffuse Large B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CTA101
PhaseEarly_Phase1
Recruitment statusRecruiting
TitlePhase I study for CTA101 Ucells injection in the treatment of relapsed or refractory CD19+ acute B-lymphocytic leukemia and diffuse large B-cell lymphoma
Year2019
CountryChina
Company sponsorThe First Affiliated Hospital of Xiamen University

Clinical Result

Cohort1: B-ALL
Administration route None
Dosage 0.1E6 cells/kg, 1E6 cells/kg, 3E6 cells/kg
Pts 9
Age Child, Adult, Older_Adult
Lymph depletion Yes
Cohort2: DLBCL
Administration route None
Dosage 0.5E6 cells/kg, 2E6 cells/kg, 3E6 cells/kg
Pts 9
Age Child, Adult, Older_Adult
Lymph depletion Yes

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