Basic Information


GTO ID GTC0718
Trial ID ACTRN12622001542785
Disease Solid Tumor
Altered gene LeY
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Lewis Y Nivo-CAR-T cells
Co-treatment Nivolumab
PhasePhase1
Recruitment statusNot Recruiting
TitleA pilot study of Lewis-Y targeting Chimeric Antigen Receptor T-cells given in combination with Nivolumab in Lewis-Y expressing solid tumours.
Year2022
CountryAustralia
Company sponsorPeter MacCallum Cancer Centre

Clinical Result

Cohort 1
Administration route None
Dosage 1E8 cells, 2E8 cells, 5E8 cells, 1E9 cells
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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