Gene symbol | IFNA2 | Synonyms | IFN-alpha-2, IFN-alphaA, IFNA, IFNA2B, leIF A | Type of gene | protein-coding |
Chromosome | 9 | Map location | 9p21.3 | dbXrefs | |
Description | interferon alpha 2 |
GTO ID | GTC0663 |
Trial ID | 2018-001741-14 |
Disease | Multiple Myeloma |
Altered gene | IFNA2 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | IFNA2 LV CD34+ cells |
Phase | Phase1|Phase2 |
Recruitment status | Prematurely Ended |
Title | A phase I/II dose escalation study evaluating safety and activity of autologous CD34+-enriched hematopoietic progenitor cells genetically modified with a lentiviral vector encoding for the human interferon-alfa2 gene in multiple myeloma patients with early relapse after intensive front line therapy |
Year | 2018 |
Country | Italy |
Company sponsor | OSPEDALE SAN RAFFAELE |
Vector information | |||
|
Cohort 1 | |||||||||
|