| Gene symbol | IFNA2 | Synonyms | IFN-alpha-2, IFN-alphaA, IFNA, IFNA2B, leIF A | Type of gene | protein-coding | |
| Chromosome | 9 | Map location | 9p21.3 | dbXrefs | Entrez:3440 MIM:147562 HGNC:HGNC:5423 Ensembl:ENSG00000188379 AllianceGenome:HGNC:5423 | |
| Description | interferon alpha 2 | |||||
| GTO ID | GTC0662 |
| Trial ID | 2018-001404-11 |
| Disease | Brain Glioblastoma Multiforme |
| Altered gene | IFNA2 |
| Therapeutic/Target gene | Therapeutic gene |
| Therapy | Gene transfer |
| Treatment | IFNA2 LV CD34+ cells |
| Phase | Phase1|Phase2 |
| Recruitment status | Ongoing |
| Title | A phase I/IIa dose escalation study evaluating the safety and efficacy of autologous CD34+-enriched hematopoietic progenitor cells genetically modified with a lentiviral vector encoding for the human interferon-α2 in patients with glioblastoma multiforme who have an unmethylated O-6- methylguanine-DNA methyltransferase gene promoter |
| Year | 2018 |
| Country | Italy |
| Company sponsor | GENENTA SCIENCE SRL |
| Vector information | |||
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| Cohort 1 | |||||||||
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