| Gene symbol | ANGPTL3 | Synonyms | ANG-5, ANGPT5, ANL3, FHBL2 | Type of gene | protein-coding |
| Chromosome | 1 | Map location | 1p31.3 | dbXrefs | |
| Description | angiopoietin like 3 | ||||
| GTO ID | GTC0641 |
| Trial ID | 2015-004003-23 |
| Disease | Familial Hypercholesterolemia |
| Altered gene | ANGPTL3 |
| Therapeutic/Target gene | Target gene |
| Therapy | ASO |
| Treatment | Vupanorsen|AKCEA ANGPTL3 LRx|IONIS ANGPTL3 LRx|ISIS 703802 salt|ISIS-703802|PF 07285557|Vupanorsen sodium |
| Phase | Phase1|Phase2 |
| Recruitment status | Completed |
| Title | A Placebo-Controlled, Dose-Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of ISIS 703802, Targeting ANGPTL3, Administered Subcutaneously to Healthy Volunteers with Elevated Triglycerides and Subjects with Familial Hypercholesterolemia |
| Year | 2016 |
| Country | Italy |
| Company sponsor | Ionis Pharmaceuticals, Inc. |
| Vector information | |||
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| Cohort 1 | |||||||
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