Gene symbol | EIF4E | Synonyms | AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q23 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | eukaryotic translation initiation factor 4E |
GTO ID | GTC0628 |
Trial ID | 2010-022240-21 |
Disease | Lung Non-Small Cell Carcinoma |
Altered gene | EIF4E |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | ISIS 183750 |
Phase | Phase1|Phase2 |
Recruitment status | Prematurely Ended |
Title | A Phase 1b/2 Study of Carboplatin-Paclitaxel, with or without ISIS 183750 (an eIF4E Inhibitor), in Patients with Stage IV Non-Small Cell Lung Cancer |
Year | 2011 |
Country | Hungary|Poland|Russian Federation|United States |
Company sponsor | Isis Pharmaceuticals Inc. |
Other ID(s) | NCT01234038 |
Vector information | |||
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Cohort 1 | |||||||
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