Gene symbol | XIAP | Synonyms | API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq25 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | X-linked inhibitor of apoptosis |
GTO ID | GTC0624 |
Trial ID | 2009-013669-25 |
Disease | Acute Myeloid Leukemia |
Altered gene | XIAP |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | AEG35156 |
Phase | Phase2 |
Recruitment status | Prematurely Ended |
Title | An Open-Label Randomized Phase 2 Study of the X-Linked Inhibitor of Apoptosis (XIAP) Antisense AEG35156 Given in Combination with High-dose Cytarabine and Idarubicin in AML Following Failure of a Single Standard Dose Cytarabine Based Frontline Induction Regimen. |
Year | 2009 |
Country | Germany |
Company sponsor | Aegera Therapeutics Inc. |
Vector information | |||
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Cohort 1 | |||||||
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