Basic Information

Gene symbol XIAP Synonyms API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description X-linked inhibitor of apoptosis

GTO ID GTC0624
Trial ID 2009-013669-25
Disease Acute Myeloid Leukemia
Altered gene XIAP
Therapeutic/Target gene Target gene
TherapyASO
Treatment AEG35156
PhasePhase2
Recruitment statusPrematurely Ended
TitleAn Open-Label Randomized Phase 2 Study of the X-Linked Inhibitor of Apoptosis (XIAP) Antisense AEG35156 Given in Combination with High-dose Cytarabine and Idarubicin in AML Following Failure of a Single Standard Dose Cytarabine Based Frontline Induction Regimen.
Year2009
CountryGermany
Company sponsorAegera Therapeutics Inc.
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 100 mg
Age Adult, Older_Adult

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