Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol TNFRSF8 Synonyms CD30, D1S166E, Ki-1 Type of gene protein-coding
Description TNF receptor superfamily member 8

GTO ID GTC0610
Trial ID ChiCTR2000028922
Disease Hodgkin's Lymphoma
Altered gene CD19|CD30
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD30 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleCD19 and CD30 CAR-T Cells Immunotherapy for Relapsing/Refractory Hodgkin's Lymphoma Patient: single center, single arm, open clinical study
Year2020
CountryChina
Company sponsorThe Third Affiliated Hospital of Kunming Medical University

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1.61e5 cells/kg, 5.2E5 cells/kg
Pts 1
Age Child, Adult, Older_Adult
Lymph depletion Yes
Outcome 1/1(SD)
Adverse reactions no any CAR-T-related severe events
References PMID: 33604290

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