Basic Information

Gene symbol CD7 Synonyms GP40, LEU-9, TP41, Tp40 Type of gene protein-coding
Description CD7 molecule

GTO ID GTC0606
Trial ID ChiCTR1900025311
Disease Hematologic Cancer
Altered gene CD7
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD7 CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleClinical research for anti-CD7 U-CAR-T bridging HST for CD7+ T/NK hematologic malignances
Year2019
CountryChina
Company sponsorThe Hematology Department of the Second Affiliated Hospital of the Army Medical University

Clinical Result

Cohort 1
Administration route None
Pts 5
Age Adult, Older_Adult
Lymph depletion Yes
Outcome 4/5(CR)
Adverse reactions Manageable CRS, no neurotoxicities, and absence of GvHD
References PMID: 34661151

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