Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC0603 |
Trial ID | ChiCTR1900023922 |
Disease | B-Cell Malignancy |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD22 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | An open-label, single-center and single-arm clinical study of infusion of anti-CD19 or CD22 CAR-T cells (CT101A-19 or CT102A-22) for patients with relapsed/refractory/high risk B cell malignancies. |
Year | 2019 |
Country | China |
Company sponsor | Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology |
Cohort 1 | |||||||||||||
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