Basic Information

Gene symbol CD7 Synonyms GP40, LEU-9, TP41, Tp40 Type of gene protein-coding
Description CD7 molecule

GTO ID GTC0534
Trial ID NCT04620655
Disease T-Cell Childhood Lymphoblastic Lymphoma | T-Cell Acute Lymphoblastic Leukemia
Altered gene CD7
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment RD13-01
Generation2nd
Recruitment statusUnknown
TitleRD13-01 for Patients With r/r CD7+ T-ALL/T-LBL
Year2020
CountryChina
Company sponsorMin Xiang
Other ID(s)BHCT-RD13-01-03

Clinical Result

Cohort 1
Administration route None
Dosage 0.5~1E7 cells/kg, 2E7 cells/kg, 4E7 cells/kg, single infusion
Donor type Allogeneic
Pts 10
Age Child, Adult, Older_Adult
Outcome 8/10(CR,28 days); 1/10(PD,28 days)
Adverse reactions 1/10 had grade 3 CRS, 1/10Experienced grade 3 neurotoxicity.
References DOI: 10.1182/blood-2022-165733

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