Administration route |
intravenous infusion |
Dosage |
0.5 E6 cells/kg, 1 E6 cells/kg |
Donor type |
Autologous |
Pts |
12 |
Age |
Adult, Older_Adult |
Lymph depletion |
Yes |
Outcome |
All patients generally reported improvement in disabilities and quality-of-life outcomes; 11 patients’ AQP-4 antibodies in serum showed a downward trend by the cutoff date. |
Adverse reactions |
The most common events of grade 3 or higher were hematologic toxic effects. 58% developed infections, but no grade 4 infections occurred. Cytokine release syndrome was reported in all patients with only events of grade 1 or 2 observed. |
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