Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
GTO ID | GTC0517 |
Trial ID | NCT04257578 |
Disease | Primary Mediastinal B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma | Follicular Lymphoma | Diffuse Large B-Cell Lymphoma Activated B-Cell Type | B-Cell Non-Hodgkin's Lymphoma | High-Grade B-Cell Lymphoma |
Altered gene | CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel |
Co-treatment | acalabrutinib |
Generation | 2nd |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma |
Year | 2020 |
Country | United States |
Company sponsor | University of Washington |
Other ID(s) | RG1006269|NCI-2020-00238|10418 |
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