Gene symbol | MSLN | Synonyms | MPF, SMRP | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mesothelin |
GTO ID | GTC0477 |
Trial ID | NCT03907852 |
Disease | Cholangiocarcinoma | Mesothelioma | Ovarian Cancer |
Altered gene | Mesothelin |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | Gavocabtagene Autoleucel|Gavo-cel|TC-210 |
Co-treatment | Nivolumab|Ipilimumab |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | A Phase 1/2 Single Arm Open-Label Clinical Trial of Gavocabtagene Autoleucel (Gavo-cel) in Patients With Advanced Mesothelin-Expressing Cancer |
Year | 2019 |
Country | United States |
Company sponsor | TCR2 Therapeutics |
Other ID(s) | TCR2-18-01 |
Vector information | |||||
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Cohort 1 | |||||||||||||||||
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