Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC0422
Trial ID NCT03455972
Disease Multiple Myeloma
Altered gene CD19|BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA/CD19 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleStudy of T Cells Targeting CD19/BCMA (CART-19/BCMA) for High Risk Multiple Myeloma Followed With Auto-HSCT
Year2018
CountryChina
Company sponsorThe First Affiliated Hospital of Soochow University
Other ID(s)myeloma-03

Clinical Result

Cohort 1
Administration route None
Dosage 1E7 cells/kg on day 0, 5E7 cells/kg, 40% on day1 and 60% on day2
Donor type Autologous
Pts 15
Age Adult, Older_Adult
Outcome 100%(ORR)

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