Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
GTO ID | GTC0370 |
Trial ID | NCT03126864 |
Disease | Acute Myeloid Leukemia |
Altered gene | CD33 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD33 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Terminated |
Title | Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia |
Year | 2017 |
Country | United States |
Company sponsor | M.D. Anderson Cancer Center |
Other ID(s) | 2016-0341|NCI-2018-01167 |
Vector information | |||||||
|
Cohort 1 | |||||||||||||
|