Gene symbol | PDCD1 | Synonyms | CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 | Type of gene | protein-coding |
Chromosome | 2 | Map location | 2q37.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | programmed cell death 1 |
GTO ID | GTC0362 |
Trial ID | NCT03081715 |
Disease | Esophageal Cancer |
Altered gene | PDCD1 |
Therapeutic/Target gene | Target gene |
Therapy | Gene editing |
Treatment | PD-1 Knockout T cells |
Phase | Not Applicable |
Recruitment status | Completed |
Title | Safety and Activity of Programmed Cell Death-1 Knockout Engineered T Cells in Patients With Previously Treated Advanced Esophageal Squamous Cell Carcinoma: An Open-label, Single-arm Phase 1 Study |
Year | 2017 |
Country | China |
Company sponsor | Hangzhou Cancer Hospital |
Other ID(s) | HangzhouCH07 |
Cohort 1 | |||||||||||||||||
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