Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC0322
Trial ID NCT02813837
Disease B-Cell Lymphoma | B-Cell Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
Recruitment statusUnknown
TitleChimeric Antigen Receptor T Cells (CART) Therapy in Refractory/Relapsed B Cell Hematologic Malignancies
Year2015
CountryChina
Company sponsorInnovative Cellular Therapeutics Co., Ltd.
Other ID(s)SCT019-01
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E5~E7 cells/kg
Donor type Autologous
Pts 35
Age Child, Adult
Lymph depletion Yes
Outcome 30/35(CR)
References PMID: 32861622

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